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Journal Article 5

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2014 1

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hand 2

and mouth disease (HFMD) 1

biped jumping 1

cell cycle 1

enterovirus 71 (EV71) 1

epidemiology 1

foot 1

foot and mouth disease 1

foot-and-mouth disease virus 1

history of machinery 1

jumping motion generation 1

management 1

pathogenesis 1

reconstruction design 1

replication 1

silk-reeling mechanism 1

stable landing control 1

structure of mechanism 1

surveillance 1

vaccine 1

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Dynamics of foot-and-mouth disease virus replication in cells at different phases of the cell-division

Claudia DOEL,Zhidong ZHANG,Lise MAZELET,Ryan WATERS,John BASHIRUDDIN

Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 3, Pages 250-257 doi: 10.15302/J-FASE-2014031

Abstract: Foot-and-mouth-disease virus (FMDV) replicates in epithelial cells.

Keywords： foot-and-mouth disease virus cell cycle replication

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Review of hand, foot and mouth disease

Lan-Juan LI MD,

Frontiers of Medicine 2010, Volume 4, Issue 2, Pages 139-146 doi: 10.1007/s11684-010-0033-6

Abstract: Hand, foot and mouth disease (HFMD) is an acute viral illness that primarily affects infants and young

Keywords： hand foot and mouth disease epidemiology pathogenesis management surveillance

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Structural synthesis of ancient Chinese foot-operated silk-reeling mechanism

Kuohung HSIAO, Yuhsun CHEN, Hongsen YAN,

Frontiers of Mechanical Engineering 2010, Volume 5, Issue 3, Pages 279-288 doi: 10.1007/s11465-010-0101-2

Abstract: This work synthesizes the structures of the foot-operated silk-reeling mechanism, which was vaguely depicted

Keywords： silk-reeling mechanism structure of mechanism reconstruction design history of machinery

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Planar jumping with stable landing through foot orientation design and ankle joint control

Qilong YUAN, I-Ming CHEN

Frontiers of Mechanical Engineering 2012, Volume 7, Issue 2, Pages 100-108 doi: 10.1007/s11465-012-0318-3

Abstract: In this work, through determining the upper body posture trajectory in the flight phase, the foot landingTogether with properly designing the trajectory for local center of gravity and the foot landing velocity

Keywords： biped jumping stable landing control jumping motion generation

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Progress on the research and development of human enterovirus 71 (EV71) vaccines

Zhenglun Liang, Qunying Mao, Fan Gao, Junzhi Wang

Frontiers of Medicine 2013, Volume 7, Issue 1, Pages 111-121 doi: 10.1007/s11684-012-0237-z

Abstract:

Enterovirus 71 (EV71) infections, which can cause severe complications, have become one of the serious public health issues in the Western Pacific region and China. To date, a number of pharmaceutical companies and institutes have initiated the research and development of EV71 vaccines as a countermeasure. As is the case with innovative vaccine development, there are several critical bottlenecks in EV71 vaccine development that must be overcome before the clinical trials, including the selection of vaccine strain, standardization of the procedure for quantifying neutralizing antibody (NTAb) and antigen, establishment and application of a reference standard and biological standards, development of animal models for the evaluation of protective efficacy, and identification of the target patient population. To tackle these technical obstacles, researchers in Mainland of China have conducted a series of studies concerning the screening of vaccine strains and the establishment of criteria, biological standards and detection methods, thereby advancing EV71 vaccine development. This review summarizes recent worldwide progress on the quality control and evaluation of EV71 vaccines.

Keywords： enterovirus 71 (EV71) hand foot and mouth disease (HFMD) vaccine